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Checked fact 109510 Oct 2026Research

Kohli, on the confidence score of AlphaFold 2, said that without calibration you "will be working on it for the next one year and finding out it was completely wrong. The calibration of the uncertainty measure was extremely important" (25:32).

The exact words it rests on

(25:15) but the PD the PLDDT score was (25:18) completely unccalibrated ... (25:26) tell you here's very very confident and (25:29) you will be working on it for the next (25:31) one year and finding out it was (25:32) completely wrong. The calibration of the (25:35) uncertainty measure was extremely (25:38) important.

What the source said when we opened it, on 10 Oct 2026.

The source

https://www.youtube.com/watch?v=NufiHZfMwaw
2026-10-09

Checked

Checked by the notis newsroom on , against the source above.

In the story

DeepMind's Kohli says replicating structures does not fully explain protein dynamics 10 Oct 2026

Said aloud in a video: the quote, word for word.

Cite this fact

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