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Checked fact 207021 Oct 2026Research

Adaptyv Bio and Twist Bioscience tested the designs by surface plasmon resonance; a binder had to be a hit at both labs (LqhIII was tested only at Adaptyv Bio), with every dissociation constant at 1 micromolar or tighter and no signal against the human protein CLEC12A.

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Both labs measured binding by surface plasmon resonance (SPR) ... The design needed to be a hit at both labs 3 ... every KD needed to be 1 µM or tighter. We also required that the design show no signal against CLEC12A ... Footnote 3: LqhIII was assessed only by Adaptyv Bio.

What the source said when we opened it, on 21 Oct 2026.

The source

How Claude designed protein binders against scorpion neurotoxins
Anthropic · 2026-10-20

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In the story

Anthropic says 17 of 211 designed proteins bound scorpion toxins in tests 21 Oct 2026

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