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Twist Bioscience

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Adaptyv Bio and Twist Bioscience tested the designs by surface plasmon resonance; a binder had to be a hit at both labs (LqhIII was tested only at Adaptyv Bio), with every dissociation constant at 1 micromolar or tighter and no signal against the human protein CLEC12A.

Both labs measured binding by surface plasmon resonance (SPR) ... The design needed to be a hit at both labs 3 ... every KD needed to be 1 µM or tighter. We also required that the design show no signal against CLEC12A ... Footnote 3: LqhIII was assessed only by Adaptyv Bio.

How Claude designed protein binders against scorpion neurotoxins · Anthropic · archived copy · checked 21 Oct 2026 · Cite this fact · the story

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Twist Bioscience

1 story · first 21 Oct · latest 21 Oct

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