Today's news

• Mistral describes Large 4, published on 6 October 2026, as a natively multimodal model with 1 trillion parameters, 49 billion of them active.
• The preview API costs $1.36 per million input tokens and $4.18 per million output tokens; Mistral says it will release the weights by the end of the month.
• Until the weights are out, Mistral says it is red-teaming the model with cybersecurity leaders, vetted partners and state authorities, who use a version with reduced moderation.

Mistral AI published Mistral Large 4 on 6 October 2026. It describes a natively multimodal model with 1 trillion parameters, 49 billion of them active. The public preview runs on the company's own infrastructure, and the listed API price is $1.36 per million input tokens and $4.18 per million output tokens. Mistral says it will release the weights by the end of the month; until then it is red-teaming the model with cybersecurity leaders, vetted partners and state authorities. The benchmark results in the post, including a rank among the top five on the Artificial Analysis Cyber Index, are Mistral's own account. It says the model was trained on 3,800 NVIDIA Grace Blackwell GPUs in its own datacenters in Europe.

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• Anthropic says the program now has three tiers, Defense, Red Team and Specialized Access, each including Claude Opus 5.5, Claude Sonnet 5.5 and Claude Mythos 5.1.
• Anthropic aims to answer Defense Access applications in a few days; Red Team Access, for organizations only, adds authorized penetration testing and is expected to take a few weeks.
• Specialized Access has the fewest cyber blocks and is for a limited set of verified organizations, each currently reviewed in depth with the US government, Anthropic says.

Anthropic announced an expanded Cyber Verification Program on 6 October 2026, built on three access tiers for qualifying security professionals. Defense Access covers defensive work such as incident response and malware reverse-engineering, and Anthropic aims to answer applications within a few days. Red Team Access adds authorized penetration testing for organizations only and is expected to take a few weeks to review. Specialized Access, with the fewest cyber blocks, is reserved for a limited set of verified organizations, and Anthropic currently reviews each one in depth with the US government. Anthropic says existing Project Glasswing members move to that tier without reapproval for current models. In its own test on CyScenarioBench, Anthropic reports that Defense Access blocked 46 of 50 trials on Claude Opus 5.5, while Red Team Access blocked none and Claude completed 34 of 50.

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• The UK government said on 6 October 2026 that it will accept all 44 recommendations of the National Commission into the Regulation of AI in Healthcare, published on 10 September.
• The MHRA is committed to issue draft guidance by December 2026 on managing changes to AI-enabled medical devices; a full roadmap of timelines and responsibilities is due by Spring 2027.
• The MHRA opened applications for the third phase of its AI Airlock sandbox; a webinar is on 22 October and the first innovators are selected in November 2026.

On 6 October 2026 the UK government confirmed it will accept all 44 recommendations of the National Commission into the Regulation of AI in Healthcare, published on 10 September. This is a government decision to act on recommendations; it does not itself change a rule. The MHRA, the UK medicines regulator, is committed to issue draft guidance by December 2026 on managing changes to AI-enabled medical devices. A full implementation roadmap will be published by Spring 2027. The MHRA also opened applications for the third phase of AI Airlock, its regulatory sandbox for AI-enabled medical devices, with the first innovators selected in November 2026.

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